Israeli research gets to the heart of the matter

(REPEL-CV est un adjuvant chirurgical indiqué pour réduire l’incidence, la gravité et l’étendue des adhérences postopératoires chez les patients âgés de moins de 21 ans qui subissent une chirurgie cardiaque et qui sont appelés à subir ultérieurement des chirurgies en plusieurs temps. REPEL-CV est un film polymère biorésorbable synthétique à usage unique qui est installé à la fin d’une chirurgie cardiaque, avant la fermeture au thorax, pour établir une barrière temporaire entre des surfaces opposées mécaniquement et les empêcher de se toucher, étant donné les adhérences fibreuses qui se forment durant les premiers stades de la réparation tissulaire. Source: Santé Canada)

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For children undergoing multiple heart surgery, the risks of vascular or cardiac injury are high. Scar tissue from previous procedures can either affect the functioning of the heart or obscure vital cardiac landmarks, making it difficult for surgeons to carry out the delicate and precise treatment required to make the operation a success.

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Now a new biomedical product developed originally at the Hebrew University of Jerusalem, could change all that. The technology, which is being commercialized by US biomaterials company SyntheMed, is a tailor-made biodegradable polymer designed to prevent scar tissue in the wake of a surgery.

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Called Repel-CV Adhesion Barrier, the product is a transparent bioresorbable film that can be inserted over the heart following open-heart surgery. The polymer, which degrades naturally, reduces the severity of scar tissue that forms between the surface of the heart and nearby tissue surfaces during the healing process. [...]

"I am very excited that the long process started several years ago in our laboratory at the Institute of Chemistry of the Hebrew University with the design and synthesis of a family of biodegradable polymers was recently approved by the FDA," said Prof. Daniel Cohn [photo], the award-winning Israeli professor who invented the polymer.

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Source: ISRAEL 21c